Walt is loyal to him and although it seems that loyalty is not 100% returned, it is. During more than a few very important and life-changing events, that loyalty was impressive and very climatic.
Poor Mr. E, he won't be able to make daily Sunday comments Gonna be a good episode tonight tho guys! I'm Excited!
I don't think there will be any need to go on without Cranston--if Jesse kills Walt (or Walt kills Jesse, or really if either of them die at all) it will probably be in the series finale.
Honestly, I try to avoid them like the plague. The Sopranos ruined me for "On the next..." montages. Ten weeks of "Oh shit, Paulie's gonna die!"
For someone who's so concerned about how Walt paid for a $300 bottle of champagne, Skyler hasn't seemed to put much thought into how they can afford an $800,000 car wash. I liked this episode. But man...Jesse's fucked.